1. Course introduction
Breast and ovarian cancer are among the most common types of cancer today, related to the inheritance of the BRCA1/2 gene mutations. BRCA1/2 are tumor suppressor genes, which help protect the body from uncontrolled growth of cells. Mutations in the BRCA1/2 genes may affect the growth inhibitory function, causing cells to proliferate uncontrollably and develop into tumors.
The course "SCREENING OF GERMLINE MUTATIONS OF BRCA 1/2 IN THE HEREDITARY BREAST AND OVARIAN CANCER SYNDROME BY NGS–ILLUMINA" is conducted by the Phacogen Institute of Technology to provide an overview of breast cancer, ovarian cancer as well as technological solutions to detect BRCA1/2 gene mutations.
The training course is designed by leading Genetics experts, offer students hands-on experience in applying the most advanced technologies in the world.
2. Teaching method
- Team-based learning: encourage critical thinking, creativity, and proactive learning through group discussions, and group presentations
- On-the-job training: Students observe and practice alongside the lecturers
- Teaching equipment: A 300 m2 Lab with modern equipment from many well-known manufacturers around the world
3. Course objectives
- Comprehend the mechanism of BRCA1/2 mutations
- Comprehend the principles of the next generation sequencing technology
- Comprehend the library preparation steps using the BRCAaccuTest kit of NGeneBio and the sequencing steps on Illumina's Miseq system
- Practice the library preparation using the BRCAaccuTest kit of NGeneBio and sequencing on Illumina's Miseq system
- Analyze test results, counsel patients
- Comprehend causes and solutions to common errors during the process
4. Syllabus
- Overview of the breast cancer diagnosis and treatment. New technological solutions applied in breast cancer diagnosis
- Overview of some next-generation gene sequencing methods, advantages and disadvantages of each method
- The principles of the next-generation gene sequencing technology on Illumina's Miseq system
- Library preparation and sequencing steps using the BRCAaccuTest kit of NGeneBio
- Analyze results on NGeneAnalySys software and create reports on analyzed data
- Course summary, Q&A, Certificate awarding ceremony
5. Course information
- Course Code: UT - 02
- Subjects: Doctors, bachelors or engineers specialized in testing in healthcare facilities; bachelors of Biology, Biotechnology, Chemistry
- Training time: 05 days (8 lessons/day)
- Number of students: 12 - 16 students per class
- Course opening: Open every month upon the number of applications
- Registration package:
- 01 Application form of Phacogen Institute of Technology HERE
- 01 notarized copy of university or college diploma
- 01 notarized copy of identity card or citizen identification